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Magnesium Malate - Supplement for Fibromyalgia

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Magnesium Malate

Soothes Muscles by Supporting Energy Production

by Source Naturals

Magnesium is an essential mineral that is necessary for the proper functioning of all muscles. It is needed by every cell of your body to help maintain normal cardiovascular, muscle, nerve, bone, and cellular function. And, it can also help relieve muscle spasms, pain, and constipation.

Malic acid is found in abundance in apples and other fruits. It is also found in the cells of plants and animals, including humans. This nutrient plays a key role in the production of energy in the cells, also known as ATP. Therefore, it is often recommended with magnesium for fibromyalgia and chronic fatigue syndrome.



Magnesium and Malic Acid for Fibromyalgia

Recent studies have indicated that those with Fibromyalgia tend to have decreased levels of magnesium in comparison to the control groups. [ 1 ] According to a study published in the Journal of Nutritional Medicine, Abraham et al hypothesized that a magnesium deficiency found in muscles cells could possibly play a role in the development of Fibromyalgia. The group demonstrated that a daily supplement of 300-600 of Magnesium Malate resulted in improvements of symptoms, as well as in the number and severity of tender points. [ 2 ]

Magnesium is an essential mineral in over 300 enzymatic reactions in metabolism. These reactions include those involved in the Krebs cycle (one of the body's energy production systems), such as:

  • DNA metabolism
  • Vital for cell formation
  • Activation of B vitamins
  • Energy transport and storage
  • The breakdown of fatty acids
  • Proper nerve function and neurotransmitter activity
  • The formation and maintenance of protein, fatty acids, and bone.
  • The formation of adenosine triphosphate (ATP), the body's energy source.

Magnesium Malate is a highly absorbable form of magnesium that provides the benefits of this mineral, along with the benefits of malic acid, a nutrient found to contribute to the process of transforming food into ATP, the body's energy source. Many fibromyalgia sufferers have stated that the combination of magnesium and malic acid have been helpful for their symptoms associated with fibromyalgia.


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Magnesium Malate and Fibromyalgia

The cause of fibromyalgia is not fully understood. However, some leading fibromyalgia researchers believe that there is a malfunction in the body's ability to manufacture energy. The muscles burn energy faster than it can be produced, which is compounded by a shortage of the nutrients necessary to make the energy. This may cause the muscles to rely too heavily on the inefficient (anaerobic) energy cycle for much of their energy production instead of the more efficient (aerobic) energy cycle. Malic acid plays a key role in the production of energy in the cells; therefore, it is often recommended with magnesium for fibromyalgia and chronic fatigue syndrome.

Magnesium Malate: A Necessity for Fibromyalgia Sufferers

Some fibromyalgia patients may be magnesium deficient. An article in the Journal of Nutritional Medicine pointed out that many fibromyalgia patients have responded quite favorably to magnesium malate. Magnesium and malic acid are important substances in the manufacture of energy for the human muscle cell.


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Case Studies: Magnesium and Malic Acid to Reduce Fibromyalgia Pain

In a 1992 study 15 fibromyalgia patients received an oral dose of 1200-2400 mg of malate (malic acid) and 300-600 mg of magnesium over a four and 8 week period. Patients reported a reduction in pain across a tender point index (TPI). Six subjects felt an improvement in 48 hours.

During another study conducted in 1995, researchers gave 24 subjects with fibromyalgia a low tablet with 50 mg magnesium and 200 mg malic acid. Scientists measured pain levels through patient self-assessment and the tender point index. Results showed that the low dose, short term trial was not effective to reduce fibromyalgia pain. However, higher doses over an extended duration significantly reduced subjects' pain.


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Clinical Trial: Magnesium Malate and Fibromyalgia

There are many people with fibromyalgia that have reported positive benefits from taking magnesium in combination with malic acid, as well as studies to back them up. For example:

In a randomized, placebo-controlled, open-label, crossover trial (grade I evidence-based), Abraham et al used a combination of magnesium (300-600 mg) and malate (1,200-2,400 mg) in 15 patients during an eight-week period. [ 3 ] The results showed a statistically significant clinical improvement (P < 0.001) in the treatment group vs. placebo as measured by two outcomes. TPI scores (± SE) of 19.6 ± 2.1 prior to treatment decreased to 8 ± 1.1 and 6.5 ± 0.74 at four and eight weeks, respectively, on the mag-malate combination. Conversely, following an average of eight weeks, six patients were switched to placebo for two weeks. Their TPI scores increased significantly (P < 0.001) from 6.8 ± 0.75 to 21.5 ± 1.4. Subjective improvement of fibromyalgia symptoms occurred within 48 hours of magnesium supplementation in the mag-malate group; symptoms worsened in the placebo group.

Many practitioners have found it to be useful in a pain reduction regimen for this disease at a higher dosage (up to 600 mg magnesium and 2,400 mg malic acid). [ 4, 5, 6 ]


More About Magnesium Malate

 

Read More About This Natural Supplement
Symptom and Supplement Reference Chart
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Supplement Facts

Capsules per Container: 200 Capsules, 625 mg
Serving Size: Six (6) Capsules
Servings per Container: 33
Suggested Use: 6 capsules daily

Supplement Facts for 625 mg Capsule
Serving Size: 6 capsule(s)
  Amount
%DV*

Calories
Total Carbohydrates
Dietary Fiber
Protein
Magnesium (as magnesium malate)
Malic Acid (as magnesium malate
and malic acid)

10
3 g
1 g
1 g
433 mg
2.5 g
**
<2%
4%
2%
110%

* Percent Daily Values (%DV) are based on a 2,000 calorie diet.
** Daily Value not established.

Other Ingredients: gelatin (capsule), microcrystalline cellulose, magnesium stearate, and colloidal silicon dioxide.

Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy, or wheat. Contains no sugar, starch, salt, preservatives, artificial colors, flavor, or fragrance.

Warning: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product. Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.

Manufactured by Source Naturals


Magnesium Malate - Supplement for Fibromyalgia

Magnesium Malate
Soothes Muscles by Supporting Energy Production
by Source Naturals
200 Capsules, 625 mg

$10.99 - Discount Price
(Retail Price $17.50 - Save 37%)

Quantity
Add to cart

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References

1. Prescott EE, et al. Red blood cell magnesium and fibromyalgia. Scand J Rheum 1992; 94:31.

2. Abraham GE, Glechas ID. Management of fibromyalgia: A rationale for the use of magnesium and malic acid. J Nutr Med 1992; 3:49-59.

3. Abraham GE, Glechas ID. Management of fibromyalgia: A rationale for the use of magnesium and malic acid. J Nutr Med 1992;3:49-59.

4. Croftord LJ, Appleton BE. Complementary and alternative therapies for fthrornyalgia. Curr Rlteurnatol Rep 2001 Apr;3(2): 147-56 Source: (http://www.tsangenterprise.com/malicmag.htm)

5. Friedberg F, Jason IA. Chronic fatigue syndrome and Palm O, Mourn B, Jahnsen J, Gran JT. Fibromyalgia and chronic widespread pain in patients with inflammatory bowel disease: a cross sectional population survey. J Rheumatol 2001 Mar;28(3):590-4

6. Russell J, Michalek J, Flechas J, et al. Treatment of fibromyalgia syndrome with SuperMalic: A randomized, double-blind, placebo-controlled, crossover pilot study. J Rheumatol 1995;22(5):953-

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